What is genotyping and 3 reasons why we use it as a way to unlock the secret of your genes

Decoding the human genome sequence is the most significant undertaking that we have mounted so far in an organised way in all of science. Francis S. Collins, Director of the National Institute of Health (NIH)

Decoding the human genome sequence is the most significant undertaking that we have mounted so far in an organised way in all of science. I believe that reading our blueprints, cataloguing our own instruction book, will be judged by history as more significant than even splitting the atom or going to the  moon.
Francis   S.   Collins Director   of   the   National   Institute   of   Health   (NIH)

The term genomics was coined with the launch of the eponymous peer-reviewed journal in 1987 and helped to distinguish science from genetics, the study of inheritance that only considered one gene at a time.

Following this, in 2003, the Human Genome Project took place with the aim of determining the sequence of human DNA and mapping all of the 3 billion genes of the human genome. It took scientists 10 years and nearly $3 billion to analyse every base pair for a single person, and it was not an easy thing to do! Then, in the mid-2000s, new forms of faster DNA sequencing allowed for the detection of variants in individuals and populations. Genotyping was born and it never stopped to become cheaper and more accurate over the years. 

Nowadays, you can have your whole genome analysed for less than $1,000 through a process called sequencing. Sequencing looks at every single one of those 3 billion base pairs in your genome in a matter of weeks. However when it comes to sequencing your whole genome, not only is it not necessarily in everyone's budget to spend that type of money on this kind of analysis, but the science to be able to interpret the entirety of your genome is not there yet. 

Consequently, based on validated science, instead of looking at all 3 billion base pairs, at Omnos we look at around 700 000 positions called single-nucleotide polymorphisms (SNPs). Our mission is to democratise the science behind health and by offering genotyping analysis, this enables us to unlock the ability to offer individual, personalised solutions toward health optimisation. Allowing each individual to regain responsibility and ownership of their own health. 

The age-old saying of one size fits all, is irrelevant now. We are all 99.9% genetically equal. But the question is, what is the 0.1% that makes you different? This is why we choose genotyping as the first step towards real personalised health

What actually is genotyping?

Even though there is a large amount of DNA that we all have in common, genotyping is the process that evaluates genetic variants/ differences of an individual within their DNA sequence. These genetic variants are important as they can lead to an observable change in a trait in a person. Which can be positive, negative or could just be a difference.

Now that we understand a bit more about genotyping, here are the 3 reasons why we use it as part of our genes test:

1. We believe in Health data ownership 

Our gene test currently looks at over 350 SNPs, covering over 500 reports across all areas of health and wellness. But your raw gene data file is also made accessible within your profile that gives you access to all of your 700k genes (Just make sure you have enough space on your computer before downloading the file!)

Health data is one of the fastest-growing commodities. At Omnos we position ourselves strongly about data ownership. Your genes, your data! We take security very seriously and work hard to make sure you have complete control over your data.  This is why we ensure you can access the raw results, request all of your data or delete your account at any time. And we will never sell or pass on your data to any other third parties. NEVER

You are in charge!

However, in the future, we might enable you to use your data asset as you wish and become the aggregator and secure platform that allows you to do so. If you choose to do so by your own consent, you may be rewarded with a better health insurance premium deal or for any other application that could benefit you, whether as a perk or even financially. This is only possible thanks to our commitment to the full access of your data at any time.

2. Ongoing updates 

One thing we know for sure is that science in the field of genomics is rapidly progressing,  and new gene-lifestyle interactions are continuously being uncovered. Within our scientific team, we process and validate all new discoveries on a constant basis. We have set internal validation processes to make sure all genes we report upon are largely validated and have subsequent references across different peer-reviewed articles. This gives us the ability to continuously update our users with new genes and the recommendations attached to them, with confidence in knowing they have strong scientific validation. This is the reason why we make the science available and clickable within each of your gene reports, as well as showing the science backing up the suggested recommendations. 

Genotyping as a process of sequencing genetic material is the only way for us to enable those ongoing updates of your genes. As an example, a new upcoming 56 genes reports are now being updated for our users about COVID19, immunity and viruses. We are doing this continuously across all topics of your health and wellness to always offer you the most complete and accurate insight into your genetic data. 

Another advantage here about genotyping is our users will never have to re-test again for you to get access to those updates.  This is because all the necessary genetic material we gather from your gene test will be genotyped and securely stored on your behalf on our secure servers in the UK. So with Omnos, you will never have to do another DNA test‍

3. The future is bright  for your genes

Science fiction writer William Gibson famously said, “The future is here. It’s just not widely distributed yet.”

When there isn’t many applications for  using all your data sets, very few are yet accessible to everyone. At Omnos we work hard to give you access to the one that will directly affect your wellbeing for the better. From personalised supplementation strategy and recommendations to your personalised food list are some great example. However it could also be used for over interesting application if you were to be opting in for them. 

Advances in DNA technology bring up fascinating questions about what role it will play in our society, from personalised medicine to the food you eat. Other application such as using DNA as a unique Identification for example.. even more accurate and secure than face detection are all possible avenue.s 

The future will tell us how much of it can be used... 

For now we are focused on democratising the science behind health , making it simple and accessible to anyone and effective to everyone,  thanks to our intelligent health system that enables optimisation through knowledge, planning and prevention, with the peace of mind that  all recommendation we make are based on validated science.

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